For the last few weeks, we've been plagued by an exploit in windows file sharing. The current worm running around is labeled worm_downad.a by Trend, conflicker by symantec and microsoft.
we're having significant trouble patching some of our systems because of the software that runs on them.
There is no such thing as a removal tool for this worm, that I can find. The solution seems to be the same for everyone: patch the system.
If you don't know what I'm talking about, you better read up. This thing gets nasty fast.